Clinical Question Which treatments for lower extremity superficial thrombophlebitis (ST) are associated with lower rates of venous thromboembolic events (VTEs) vs placebo?. Di Minno MND et al. (superficial thrombophlebitis) or axial veins (ie, great or small saphenous veins) indicative of superficial vein thrombosis (SVT), and whether or not there are complications. Superficial venous thrombosis and venous thromboembolism: a large, prospective epidemiologic study. The vein becomes inflamed because there's blood clotting inside it or the vein walls are damaged. The treatment of superficial thrombophlebitis depends on the cause and the type and severity of the symptoms present. The optimal treatment of superficial thrombophlebitis (ST) of the legs remains poorly defined. What are the symptoms? However, given th … Patients with superficial vein thrombosis (SVT) are commonly treated with low-molecular weight heparin or fondaparinux in prophylactic, intermediate or therapeutic dosages for treatment periods of 10-45 days. In superficial thrombophlebitis of the legs, a short course (4 weeks duration) with a medication that reduces the blood clotting power of the body is generally recommended. The risk of DVT in a patient with superficial thrombophlebitis is remote. Approach to treatment —Treatment of superficial phlebitis is primarily aimed at alleviating symptoms and preventing propagation of thrombus into the deep venous system. Prevalence of deep vein thrombosis and pulmonary embolism in patients with superficial vein thrombosis: a systematic review and meta-analysis. Topical heparin for the treatment of acute superficial phlebitis secondary to indwelling intravenous catheter. One case-series study found that it occurred very occasionally if the thrombophlebitis extended above the knee.4 The clinical evaluation of patients with suspected DVT A double-blind, randomized, placebocontrolled trial. This treatment has been shown to reduce the 5 mg/kg once daily, or tenoxicam 20 mg/day or placebo for 8 to 12 days. Treatment with a clot-dissolving drug is called thrombolysis. Treatment effect was evaluated using the status of thrombophlebitis, the thrombophlebitic area, pain intensity with a visual analogue scale, and side effects were registered. Most superficial veins that develop thrombosis also have phlebitis, in contrast to deep venous thrombosis, a sometimes asymptomatic condition in which phlebitis may be absent. Bottom Line A dose of 2.5 mg of fondaparinux administered subcutaneously once daily for 45 days is associated with fewer cases of symptomatic VTE without an increase in major bleeding vs placebo. 2 J Vasc Bras. Superficial thrombophlebitis is a common inflammatory-thrombotic disorder in which a thrombus develops in a vein located near the surface of the skin. For superficial thrombophlebitis, your doctor might recommend applying heat to the painful area, elevating the affected leg, using an over-the-counter nonsteroidal anti-inflammatory drug (NSAID) and possibly wearing compression stockings. a prior history of superficial thrombophlebitis and/or DVT. 87. Treatment of superficial thrombophlebitis: a randomized, bouble-blind trial of heparinoid cream. This practice is also reflected by the current guideline recommendations. Phlebitis means "inflammation of a vein". Br J Med. ; 14(1):1-3 Complications and treatment of superficial thrombophlebitis The miscellany of conflicting results is reflected in the consensus guidelines on treating the condition. Decousus H et al. 2015 Jan.-Mar. Annals of Internal Medicine 2010;152(4):218-24. Vilardell M, Sabat D, Arnaiz JA, et al. 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